Author: Malcolm Low

Dr. Malcolm Low is currently an Associate Professor with the Singapore Institute of Technology (SIT).

There may soon be a new approach to treat hard-to-control high blood pressure | CNN

https://www.cnn.com/2025/08/30/health/blood-pressure-medicine-baxdrostat

The researchers on the new trial placed the participants into three groups. One received 1 milligram of baxdrostat, another got 2 mg, and another got a placebo, which does nothing. Participants took their dose in addition to medicines they were already taking.

At 12 weeks, about 4 in 10 patients taking baxdrostat reached healthy blood pressure levels, compared with less than 2 in 10 who got a placebo.

Specifically, participants who got 1 or 2 mg of baxdrostat daily saw their systolic blood pressure – the upper number in the reading – fall around 9 to 10 mm Hg more than those taking a placebo. This reduction, studies show, is large enough to cut cardiovascular risk.

Custom AI Tutor Bots Are Transforming Learning at HBS

Here’s How Students Are Using Them.
https://hbsp.harvard.edu/inspiring-minds/ai-tutor-bots-harvard-business-school?cid=email%7Cmarketo%7C2025-08-05-the-faculty-lounge%7C16909341%7Cfaculty-lounge-newsletter%7Ceducator%7Cvarious%7Caug2025&acctID=19108014&mkt_tok=ODU1LUFUWi0yOTQAAAGcGOJuk5dUK_bfYAJspUPzDy23I1LIKFXdrYcYPEneo2U2QCYLKRaRXSw20-AuQ96k9B45n2Kuk0jV9_5jAw7mDbRPRnomJPBDMVJ82ItxmJALSg

Encouraged by these early successes, HBS faculty and the Digital Transformation team are expanding AI experiments throughout the curriculum; this includes integrating HBS-developed tutor bots in more courses in the future, such as data science, finance, and strategy. HBS is also giving all students access to general-purpose AI tools, including ChatGPT Edu and the data analysis tool Julius AI, to further promote AI usage among students.

Mathematical Patterns: The Curious Case of 1/998001

Mathematics reveals elegant patterns in unexpected places. Consider 1/998001, which equals 0.000001002003004… containing every three-digit number in sequence.

This occurs because 998001 = 999². Similar patterns emerge in related fractions:

  • 1/9 = 0.111111…
  • 1/99 = 0.010101…
  • 1/999 = 0.001001001…

These numerical sequences demonstrate that mathematics is not merely computational but reveals fundamental structures underlying our universe. Such patterns have practical applications in algorithm development, cryptography, and data analysis.

The ordered nature of these mathematical curiosities reminds us that even within apparent complexity, we can discover remarkable simplicity and structure.

Automating oral argument

Back in January 2023, a company called DoNotPay offered “any lawyer or person $1,000,000 with an upcoming case in front of the United States Supreme Court to wear AirPods and let our robot lawyer argue the case by repeating exactly what it says.” At the time, everyone thought this was a silly gimmick.

https://adamunikowsky.substack.com/p/automating-oral-argument?utm_source=tldrai